Anti-TRPM7 / LTRPC7, clone S74-25

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG22280.50	50 µg		-	-	6 - 14 business days*		520.00€

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Protein function: Essential ion channel and serine/threonine-protein kinase. Divalent cation... more

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Product information "Anti-TRPM7 / LTRPC7, clone S74-25"

Protein function: Essential ion channel and serine/threonine-protein kinase. Divalent cation channel permeable to calcium and magnesium. Has a central role in magnesium ion homeostasis and in the regulation of anoxic neuronal cell death. Involved in TNF- induced necroptosis downstream of MLKL by mediating calcium influx. The kinase activity is essential for the channel function. May be involved in a fundamental process that adjusts plasma membrane divalent cation fluxes according to the metabolic state of the cell. Phosphorylates annexin A1 (ANXA1). [The UniProt Consortium]

Keywords:	Anti-Chak, Anti-Trpm7, Anti-LTrpC7, Anti-LTrpC-7, Anti-TRP-PLIK, EC=2.7.11.1, Anti-Channel-kinase 1, Anti-Long transient receptor potential channel 7, Anti-Transient receptor potential-phospholipase C-interacting kinase
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG22280

Properties

Application:	WB, IHC, ICC, IF
Antibody Type:	Monoclonal
Clone:	S74-25
Conjugate:	No
Host:	Mouse
Species reactivity:	human, mouse, rat
Immunogen:	Fusion protein around aa. 1817-1863 (C- terminus) of Mouse TrpM7
MW:	220 kD
Format:	Purified