Anti-TRPM7

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A302-700A-T	10 µl (2 µg)		-		2 - 8 business days*		165.00€
A302-700A	100 µl		-		2 - 8 business days*		586.00€

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Protein function: Essential ion channel and serine/threonine-protein kinase. Divalent cation... more

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Product information "Anti-TRPM7"

Protein function: Essential ion channel and serine/threonine-protein kinase. Divalent cation channel permeable to calcium and magnesium. Has a central role in magnesium ion homeostasis and in the regulation of anoxic neuronal cell death. Involved in TNF- induced necroptosis downstream of MLKL by mediating calcium influx. The kinase activity is essential for the channel function. May be involved in a fundamental process that adjusts plasma membrane divalent cation fluxes according to the metabolic state of the cell. Phosphorylates annexin A1 (ANXA1). [The UniProt Consortium]

Keywords:	Anti-CHAK1, Anti-TRPM7, Anti-LTrpC7, Anti-LTrpC-7, EC=2.7.11.1, Anti-Channel-kinase 1, Anti-Long transient receptor potential channel 7, Anti-Transient receptor potential cation channel subfamily M member 7
Supplier:	Bethyl Laboratories
Supplier-Nr:	A302-700A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse (Expected: rabbit, guinea pig_10141, pig, orangutan, rhesus monkey, chimpanzee, root node of taxonomy, white-tufted-ear marmoset, crab-eating macaque, naked mole rat, small-eared galago, northern white-cheeked gibbon)
Immunogen:	synthetic peptide. The epitope recognized by A302-700A-T maps to a region between residue 1815 and 1865 of human transient receptor potential cation channel, subfamily M, member 7 using the numbering given in entry NP_060142.3 (GeneID 54822).
Format:	Antigen Affinity Purified