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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
600-401-FQ3 | 100 µg | - | - |
6 - 10 business days* |
684.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Anti-TRPC3 Antibody was affinity purified from monospecific antiserum by immunoaffinity... more
Product information "Anti-TRPC3"
Anti-TRPC3 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with TRPC3 from other sources has not been determined. Protein function: Capsid-specific restriction factor that prevents infection from non-host-adapted retroviruses. Blocks viral replication early in the life cycle, after viral entry but before reverse transcription. In addition to acting as a capsid-specific restriction factor, also acts as a pattern recognition receptor that activates innate immune signaling in response to the retroviral capsid lattice. Binding to the viral capsid triggers its E3 ubiquitin ligase activity, and in concert with the heterodimeric ubiquitin conjugating enzyme complex UBE2V1-UBE2N (also known as UBC13-UEV1A complex) generates 'Lys-63'-linked polyubiquitin chains, which in turn are catalysts in the autophosphorylation of the MAP3K7/TAK1 complex (includes TAK1, TAB2, and TAB3). Activation of the MAP3K7/TAK1 complex by autophosphorylation results in the induction and expression of NF- kappa-B and MAPK-responsive inflammatory genes, thereby leading to an innate immune response in the infected cell. Restricts infection by N-tropic murine leukemia virus (N-MLV) and equine infectious anemia virus (EIAV). [The UniProt Consortium]
Keywords: | Anti-RNF88, Anti-TRIM5, EC=6.3.2.-, Anti-RING finger protein 88, Anti-Tripartite motif-containing protein 5 |
Supplier: | Rockland Immunochemicals |
Supplier-Nr: | 600-401-FQ3 |
Properties
Application: | ELISA, IHC, WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse |
Immunogen: | 14 amino acid synthetic peptide from near the N-terminus of human TRPC3. |
Format: | Purified |
Database Information
KEGG ID : | K10648 | Matching products |
UniProt ID : | Q9C035 | Matching products |
Gene ID | GeneID 85363 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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