Anti-TRIM50

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA019862.25	25 µl		-		7 - 10 business days*		246.00€
ATA-HPA019862.100	100 µl		-		7 - 10 business days*		491.00€

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Protein function: E3 ubiquitin-protein ligase that ubiquitinates Beclin-1/BECN1 in a... more

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Product information "Anti-TRIM50"

Protein function: E3 ubiquitin-protein ligase that ubiquitinates Beclin-1/BECN1 in a 'Lys-63'-dependent manner enhancing its binding to ULK1. In turn, promotes starvation-induced autophagy activation. Interacts also with p62/SQSTM1 protein and thereby induces the formation and the autophagy clearance of aggresome-associated polyubiquitinated proteins through HDAC6 interaction. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 93% and to rat: 95%

Keywords:	Anti-TRIM50, Anti-TRIM50A, Anti-E3 ubiquitin-protein ligase TRIM50, Anti-Tripartite motif-containing protein 50, Anti-RING-type E3 ubiquitin transferase TRIM50
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA019862

Properties

Application:	IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: AFSPISFKPG LHQADIKLTV WKRLFRKVLP APEPLKLDPA TAHPLLELSK GNTVVQCGLL AQRRASQPER FDYSTC (ATA-APrEST75005)