Anti-TRIM33

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA004345.25	25 µl		-		7 - 10 business days*		246.00€
ATA-HPA004345.100	100 µl		-		7 - 10 business days*		491.00€

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Protein function: Acts as an E3 ubiquitin-protein ligase. Promotes SMAD4 ubiquitination, nuclear... more

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Product information "Anti-TRIM33"

Protein function: Acts as an E3 ubiquitin-protein ligase. Promotes SMAD4 ubiquitination, nuclear exclusion and degradation via the ubiquitin proteasome pathway. According to PubMed:16751102, does not promote a decrease in the level of endogenous SMAD4. May act as a transcriptional repressor. Inhibits the transcriptional response to TGF-beta/BMP signaling cascade. Plays a role in the control of cell proliferation. Its association with SMAD2 and SMAD3 stimulates erythroid differentiation of hematopoietic stem/progenitor. Monoubiquitinates SMAD4 and acts as an inhibitor of SMAD4-dependent TGF-beta/BMP signaling cascade (Monoubiquitination of SMAD4 hampers its ability to form a stable complex with activated SMAD2/3 resulting in inhibition of TGF-beta/BMP signaling cascade). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 98% and to rat: 98%

Keywords:	Anti-TRIM33, Anti-KIAA1113, Anti-TIF1-gamma, EC=2.3.2.27, Anti-Protein Rfg7, Anti-Ectodermin homolog, Anti-RET-fused gene 7 protein, Anti-E3 ubiquitin-protein ligase TRIM33, Anti-Tripartite motif-containing protein 33
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA004345

Properties

Application:	WB, IHC, ICC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: MQPHLQRQHS NPGHAGPFPV VSVHNTTINP TSPTTATMAN ANRGPTSPSV TAIELIPSVT NPENLPSLPD IPPIQLEDAG SSSLDNLLSR YISGSHLPPQ PTSTMNPSPG PSALSPGSSG LSNSHTPVRP PSTSSTGSR (ATA-APrEST86693)