Anti-TRIM29

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA020053.25	25 µl		-		7 - 10 business days*		330.00€
ATA-HPA020053.100	100 µl		-		7 - 10 business days*		463.00€

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Protein function: Plays a crucial role in the regulation of macrophage activation in response to... more

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Product information "Anti-TRIM29"

Protein function: Plays a crucial role in the regulation of macrophage activation in response to viral or bacterial infections within the respiratory tract. Mechanistically, TRIM29 interacts with IKBKG/NEMO in the lysosome where it induces its 'Lys-48' ubiquitination and subsequent degradation. In turn, the expression of type I interferons and the production of proinflammatory cytokines are inhibited. Additionally, induces the 'Lys-48' ubiquitination of STING1 in a similar way, leading to its degradation. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 87% and to rat: 87%

Keywords:	Anti-ATDC, Anti-TRIM29, Anti-Tripartite motif-containing protein 29, Anti-Ataxia telangiectasia group D-associated protein
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA020053

Properties

Application:	ICC, IHC, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, rat
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: GDDKNSNYFS MDSMEGKRSP YAGLQLGAAK KPPVTFAEKG ELRKSIFSES RKPTVSIMEP GETRRNSYPR ADTGLFSRSK SGSEEVLCDS CIGNKQKAVK SCLVCQASFC ELHL (ATA-APrEST86839)