Anti-TRIM23

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA039605.25	25 µl		-		7 - 10 business days*		246.00€
ATA-HPA039605.100	100 µl		-		7 - 10 business days*		491.00€

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Protein function: Acts as an E3 ubiquitin-protein ligase. Plays an essential role in autophagy... more

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Product information "Anti-TRIM23"

Protein function: Acts as an E3 ubiquitin-protein ligase. Plays an essential role in autophagy activation during viral infection. Mechanistically, activates TANK-binding kinase 1/TBK1 by facilitating its dimerization and ability to phosphorylate the selective autophagy receptor SQSTM1. In order to achieve this function, TRIM23 mediates 'Lys-27'-linked auto-ubiquitination of its ADP-ribosylation factor (ARF) domain to induce its GTPase activity and its recruitment to autophagosomes (PubMed:28871090). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 92% and to rat: 94%

Keywords:	Anti-ARD1, Anti-TRIM23, EC=2.3.2.27, Anti-RING finger protein 46, Anti-GTP-binding protein ARD-1, Anti-E3 ubiquitin-protein ligase TRIM23, Anti-Tripartite motif-containing protein 23, Anti-RING-type E3 ubiquitin transferase TRIM23
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA039605

Properties

Application:	IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: LGDSGVWGLK KNFALLELLE RLQNGPIGQY GAAEESIGIS GESITRCDED EAHLASVYCT VCATHLCSEC SQVTHST (ATA-APrEST79961)