Anti-TRI10

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ELK-ES19400.50	50 µl		-	-	10 - 14 business days*		173.00€
ELK-ES19400.100	100 µl		-	-	10 - 14 business days*		290.00€

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Protein function: E3 ligase that plays an essential role in the differentiation and survival of... more

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Product information "Anti-TRI10"

Protein function: E3 ligase that plays an essential role in the differentiation and survival of terminal erythroid cells. May directly bind to PTEN and promote its ubiquitination, resulting in its proteasomal degradation and activation of hypertrophic signaling. In addition, plays a role in immune response regulation by repressing the phosphorylation of STAT1 and STAT2 in the interferon/JAK/STAT signaling pathway independent of its E3 ligase activity. Mechanistically, interacts with the intracellular domain of IFNAR1 and thereby inhibits the association between TYK2 and IFNAR1 (PubMed:33811647). [The UniProt Consortium] Recommended dilutions: WB 1:1000-2000. Cellular localization: Cytoplasm .

Keywords:	Anti-RFB30, Anti-TRIM10, Anti-RING finger protein 9, Anti-B30-RING finger protein, Anti-Tripartite motif-containing protein 10, TRI10 rabbit pAb
Supplier:	ELK Biotechnology
Supplier-Nr:	ES19400

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse
Immunogen:	Synthesized peptide derived from human TRI10 AA range: 319-369
Format:	Purified