Anti-TREK1 (Twik-Related Potassium Channel 1, Kcnk2)

Anti-TREK1 (Twik-Related Potassium Channel 1, Kcnk2)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
T8280-01.100 100 µl - -

4 - 22 business days

539.00€
 
TREK-1 is a two-pore-domain background potassium channel expressed throughout the central nervous... more
Product information "Anti-TREK1 (Twik-Related Potassium Channel 1, Kcnk2)"
TREK-1 is a two-pore-domain background potassium channel expressed throughout the central nervous system. It is opened by polyunsaturated fatty acids and lysophospholipids. As well, it is regulated by various neurotransmitters. It has been shown that alterations in the functioning, regulation, or both of the TREK-1 channel may alter mood. TREK-1 is also activated by volatile anesthetics and has been suggested to be an important target in the action of these drugs. Therefore, this particular K+ channel emerges as a potential innovative target for developing new therapeutic agents for anesthesiology and neurology, such as antidepressants. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilutions: Western Blot: 2ug/ml. Esssential to run against membrane preps., Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-TREK-1 K() channel subunit, Anti-Two pore potassium channel TPKC1, Anti-Potassium channel subfamily K member 2, Anti-Two pore domain potassium channel TREK-1, Anti-Outward rectifying potassium channel protein TREK-1
Supplier: United States Biological
Supplier-Nr: T8280-01

Properties

Application: WB
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human
Immunogen: Synthetic peptide within the N-terminal region [residues 1-100] of the human TREK 1 protein [Swiss-Prot# Q9NRT2]
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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