Anti-TRAM2 [R01-7F4] Monoclonal Antibody

TRAM2 Monoclonal Antibody from Assay Genie is a high quality antibody for research use only. Protein Function: Necessary for collagen type I synthesis. May couple the activity of the ER Ca(2+) pump SERCA2B with the activity of the translocon. This coupling may increase the local Ca(2+) concentration at the site of collagen synthesis, and a high Ca(2+) concentration may be necessary for the function of molecular chaperones involved in collagen folding. Required for proper insertion of the first transmembrane helix N-terminus of TM4SF20 into the ER lumen, may act as a ceramide sensor for regulated alternative translocation (RAT) (PubMed:27499293) [The Uniprot Consortium]