Anti-TRAM2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG59717.100	100 µl		-	-	6 - 14 business days*		658.00€

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Protein function: Necessary for collagen type I synthesis. May couple the activity of the ER... more

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Product information "Anti-TRAM2"

Protein function: Necessary for collagen type I synthesis. May couple the activity of the ER Ca(2+) pump SERCA2B with the activity of the translocon. This coupling may increase the local Ca(2+) concentration at the site of collagen synthesis, and a high Ca(2+) concentration may be necessary for the function of molecular chaperones involved in collagen folding. Required for proper insertion of the first transmembrane helix N-terminus of TM4SF20 into the ER lumen, may act as a ceramide sensor for regulated alternative translocation (RAT) (PubMed:27499293). [The UniProt Consortium]

Keywords:	Anti-TRAM2, Anti-KIAA0057, Anti-Translocating chain-associated membrane protein 2
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG59717

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Synthetic peptide derived from Human TRAM2
MW:	43 kD
Format:	Affinity Purified