Anti-TRAIL Receptor-3 (TRAIL R3, TNF-Related Apoptosis Inducing Receptor3)

TRAIL (also known as Apo-2L) is a member of the tumor necrosis factor (TNF) ligand family that rapidly induces apoptosis in a variety of transformed cell lines. A distinct receptor for TRAIL, TRAIL-R3, is restricted to peripheral blood lymphocytes (PBLs) and skeletal muscle. All three TRAIL receptors bind TRAIL with similar af?nity, suggesting a complex regulation of TRAIL-mediated signals., , Applications: , Suitable for use in Western Blot, ELISA. Other applications have not been tested. Recommended Dilution: Western Blot: 1:250-1:500, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.