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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ARG54683.50 | 50 µg | - | - |
6 - 14 business days* |
520.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the... more
Product information "Anti-TRAF6"
Protein function: E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, IRAK1, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Leads to the activation of NF-kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c- Myb-mediated transactivation, in B-lymphocytes. Adapter protein that seems to play a role in signal transduction initiated via TNF receptor, IL-1 receptor and IL-17 receptor. Regulates osteoclast differentiation by mediating the activation of adapter protein complex 1 (AP-1) and NF-kappa-B, in response to RANK-L stimulation. Together with MAP3K8, mediates CD40 signals that activate ERK in B-cells and macrophages, and thus may play a role in the regulation of immunoglobulin production. [The UniProt Consortium]
Keywords: | Anti-RNF85, Anti-TRAF6, EC=6.3.2.-, Anti-RING finger protein 85, Anti-Interleukin-1 signal transducer, Anti-TNF receptor-associated factor 6, Anti-E3 ubiquitin-protein ligase TRAF6 |
Supplier: | Arigo Biolaboratories |
Supplier-Nr: | ARG54683 |
Properties
Application: | ELISA, WB, ICC, IF |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | Stnthetic peptide around 14 aa (C-terminus) of Human TRAF6 protein (NP_004611.1) |
Format: | Purified |
Database Information
KEGG ID : | K03175 | Matching products |
UniProt ID : | Q9Y4K3 | Matching products |
Gene ID | GeneID 7189 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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