Anti-TRAF3IP2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA036352.25	25 µl		-		7 - 10 business days*		246.00€
ATA-HPA036352.100	100 µl		-		7 - 10 business days*		491.00€

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Protein function: E3 ubiquitin ligase that catalyzes 'Lys-63'-linked polyubiquitination of target... more

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Product information "Anti-TRAF3IP2"

Protein function: E3 ubiquitin ligase that catalyzes 'Lys-63'-linked polyubiquitination of target protein, enhancing protein-protein interaction and cell signaling (PubMed:19825828). Transfers ubiquitin from E2 ubiquitin-conjugating enzyme UBE2V1-UBE2N to substrate protein (PubMed:19825828). Essential adapter molecule in IL17A-mediated signaling (PubMed:19825828, PubMed:24120361). Upon IL17A stimulation, interacts with IL17RA and IL17RC receptor chains through SEFIR domains and catalyzes 'Lys-63'-linked polyubiquitination of TRAF6, leading to TRAF6-mediated activation of NF-kappa-B and MAPkinase pathways (PubMed:19825828). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 99% and to rat: 96%

Keywords:	Anti-ACT1, Anti-C6orf2, Anti-TRAF3IP2, Anti-Adapter protein CIKS, Anti-TRAF3-interacting protein 2, Anti-E3 ubiquitin ligase TRAF3IP2, Anti-Connection to IKK and SAPK/JNK, Anti-E3 ubiquitin-protein ligase CIKS, Anti-Nuclear factor NF-kappa-B activator 1
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA036352

Properties

Application:	WB, IHC, ICC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: KQDVEGAESQ LDEDEHGLHT KYIHRMMQIE FIKQGSMNFR FIPVLFPNAK KEHVPTWLQN THVYSWPKNK KNILLRLLR (ATA-APrEST77277)