Anti-TRAF3IP2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-KC-36453.50	50 µl		-	-	Request delivery time estimate		206.00€
ABS-KC-36453.100	100 µl		-	-	Request delivery time estimate		295.00€

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Protein function: E3 ubiquitin ligase that catalyzes 'Lys-63'-linked polyubiquitination of target... more

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Product information "Anti-TRAF3IP2"

Protein function: E3 ubiquitin ligase that catalyzes 'Lys-63'-linked polyubiquitination of target protein, enhancing protein-protein interaction and cell signaling (PubMed:19825828). Transfers ubiquitin from E2 ubiquitin-conjugating enzyme UBE2V1-UBE2N to substrate protein (PubMed:19825828). Essential adapter molecule in IL17A-mediated signaling (PubMed:19825828, PubMed:24120361). Upon IL17A stimulation, interacts with IL17RA and IL17RC receptor chains through SEFIR domains and catalyzes 'Lys-63'-linked polyubiquitination of TRAF6, leading to TRAF6-mediated activation of NF-kappa-B and MAPkinase pathways (PubMed:19825828). [The UniProt Consortium]

Keywords:	Anti-ACT1, Anti-C6orf2, Anti-TRAF3IP2, Anti-Adapter protein CIKS, Anti-TRAF3-interacting protein 2, Anti-E3 ubiquitin ligase TRAF3IP2, Anti-Connection to IKK and SAPK/JNK, Anti-E3 ubiquitin-protein ligase CIKS, Anti-Nuclear factor NF-kappa-B activator 1
Supplier:	Absea
Supplier-Nr:	KC-36453

Properties

Application:	WB
Antibody Type:	Monoclonal
Clone:	K94092_19D6
Conjugate:	No
Host:	Mouse
Species reactivity:	human
Immunogen:	recombinant human TRAF3IP2
Format:	Solution

Database Information

KEGG ID :	K21124 \| Matching products
UniProt ID :	O43734 \| Matching products
Gene ID :	GeneID 10758 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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