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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ABS-OC-144.50 | 50 µl | - | - |
Request delivery time estimate |
206.00€
|
||
| ABS-OC-144.100 | 100 µl | - | - |
Request delivery time estimate |
295.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Acts as a sequence specific DNA binding transcriptional activator or repressor.... more
Product information "Anti-TP63"
Protein function: Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. Isoform 2 activates RIPK4 transcription. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. Involved in Notch signaling by probably inducing JAG1 and JAG2. Plays a role in the regulation of epithelial morphogenesis. The ratio of DeltaN-type and TA*-type isoforms may govern the maintenance of epithelial stem cell compartments and regulate the initiation of epithelial stratification from the undifferentiated embryonal ectoderm. Required for limb formation from the apical ectodermal ridge. Activates transcription of the p21 promoter. [The UniProt Consortium]
| Keywords: | Anti-Tumor protein 63, Anti-p63, Anti-Chronic ulcerative stomatitis protein, Anti-CUSP, Anti-Keratinocyte transcription factor KET, Anti-Transformation-related protein 63, Anti-TP63, Anti-Tumor protein p73-like, Anti-p73L, Anti-p40, Anti-p51, TP63 Antibod |
| Supplier: | Absea |
| Supplier-Nr: | OC-144 |
Properties
| Application: | IHC |
| Antibody Type: | Mixed |
| Conjugate: | No |
| Host: | Mouse |
| Species reactivity: | human |
| Immunogen: | Recombinant human TP63 |
| Format: | Solution |
Database Information
| KEGG ID : | K10149 | Matching products |
| UniProt ID : | Q9H3D4 | Matching products |
| Gene ID : | GeneID 8626 | Matching products |
Handling & Safety
| Storage: | -20°C (avoid repeat freezing and thawing cycles) |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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