Anti-TP53BP2 / ASPP2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG41886.100	100 µl		-	-	6 - 14 business days*		624.00€

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Protein function: Regulator that plays a central role in regulation of apoptosis and cell growth... more

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Product information "Anti-TP53BP2 / ASPP2"

Protein function: Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions with proteins such as TP53 (PubMed:12524540). Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42. [The UniProt Consortium]

Keywords:	Anti-Bbp, Anti-ASPP2, Anti-53BP2, Anti-p53BP2, Anti-TP53BP2, Anti-Bcl2-binding protein, Anti-p53-binding protein 2, Anti-Renal carcinoma antigen NY-REN-51, Anti-Tumor suppressor p53-binding protein 2, Anti-Apoptosis-stimulating of p53 protein 2
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG41886

Properties

Application:	ICC, IF, IHC (paraffin)
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Recombinant fusion protein corresponding to aa. 360-600 of Human TP53BP2 / ASPP2. (NP_001026855.2)
Format:	Affinity Purified