Anti-TOX3 / TNRC9, clone TOX3/1123

Formulation: Purified Ab with BSA and Azide at 200ug/ml. Cellular Localization: Nucleus. Positive Control: A431 cell lysate (WB). Human breast or gastric carcinoma (IHC). Chromosome Location: 16q12.1. Protein Function: Transcriptional coactivator of the p300/CBP-mediated transcription complex. Activates transactivation through cAMP response element (CRE) sites. Protects against cell death by inducing antiapoptotic and repressing pro-apoptotic transcripts. Stimulates transcription from the estrogen-responsive or BCL-2 promoters. Required for depolarization-induced transcription activation of the C-FOS promoter in neurons. Associates with chromatin to the estrogen-responsive C3 promoter region [The Uniprot Consortium]