Anti-TOMM70

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA048020.25	25 µl		-		3 - 8 business days*		246.00€
ATA-HPA048020.100	100 µl		-		3 - 8 business days*		491.00€

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Protein function: Acts as receptor of the preprotein translocase complex of the outer... more

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Product information "Anti-TOMM70"

Protein function: Acts as receptor of the preprotein translocase complex of the outer mitochondrial membrane (TOM complex). Recognizes and mediates the translocation of mitochondrial preproteins from the cytosol into the mitochondria in a chaperone dependent manner (PubMed:12526792). Mediates TBK1 and IRF3 activation induced by MAVS in response to Sendai virus infection and promotes host antiviral responses during virus infection (PubMed:20628368, PubMed:25609812). Upon Sendai virus infection, recruits HSP90AA1:IRF3:BAX in mitochondrion and the complex induces apoptosis (PubMed:25609812). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 98% and to rat: 98%

Keywords:	Anti-KIAA0719, Anti-Mitochondrial import receptor subunit TOM70, Anti-Translocase of outer membrane 70 kDa subunit, Anti-Mitochondrial precursor proteins import receptor, Anti-Translocase of outer mitochondrial membrane protein 70
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA048020

Properties

Application:	WB, IHC, ICC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: YTEAISLCPT EKNVDLSTFY QNRAAAFEQL QKWKEVAQDC TKAVELNPKY VKALFRRAKA HEKLDNKKEC LEDVTAVCIL EGFQNQQSML LADKVLKLLG KEKAKEKYKN REPLMPSPQF IKS (ATA-APrEST87494)