Anti-TOLLIP

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA038621.25	25 µl		-		3 - 8 business days*		246.00€
ATA-HPA038621.100	100 µl		-		3 - 8 business days*		491.00€

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Protein function: Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits... more

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Product information "Anti-TOLLIP"

Protein function: Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity (PubMed:11751856). Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin-ATG8 family adapter and thus mediating autophagic clearance of ubiquitin conjugates. The TOLLIP- dependent selective autophagy pathway plays an important role in clearance of cytotoxic polyQ proteins aggregates (PubMed:25042851). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 88% and to rat: 88%

Keywords:	Anti-TOLLIP, Anti-Toll-interacting protein
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA038621

Properties

Application:	ICC, IHC, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, rat
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: VEDKWYSLSG RQGDDKEGMI NLVMSYALLP AAMVMPPQPV VLMPTVYQQG VGYVPITGMP AVCSPGMVPV ALPPAAVNAQ PRCSEEDLKA (ATA-APrEST80485)