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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-V3636-20UG | 20 µg | - | - |
3 - 10 business days* |
332.00€
|
||
NSJ-V3636-100UG | 100 µg | - | - |
3 - 10 business days* |
752.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide. TNF ligand-related... more
Product information "Anti-TNFSF15 / VEGI / TL1A, clone VEGI/2052R"
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide. TNF ligand-related molecule 1 is an anti-angiogenic cytokine that is also called Tumor necrosis factor superfamily, member 15 (TNFSF15) and Vascular endothelial growth inhibitor (VEGI/VEGI192A). This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Reduced expression of TL1A/TNFSF15/VEGI has been reported as a marker of poor prognosis in breast cancer. Protein function: Receptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis. [The UniProt Consortium]
Keywords: | Anti-TL1, Anti-TNFSF15, TNFSF15 Antibody / VEGI / TL1A |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | V3636 |
Properties
Application: | IHC (paraffin) |
Antibody Type: | Monoclonal |
Clone: | VEGI/2052R |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | A full length human recombinant protein was used as the immunogen for this recombinant TNFSF15 antibody. |
Format: | Purified |
Database Information
KEGG ID : | K05478 | Matching products |
UniProt ID : | O95150 | Matching products |
Gene ID | GeneID 9966 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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