Anti-TNFRSF1B antibody(8C4), IgG1 Chimeric mAb

Item number	Size	Manual	SDS	Delivery time	Price
DIM-DMC101037.10	10 µg	-	-	7 - 16 business days*	145.00€
DIM-DMC101037.100	100 µg	-	-	7 - 16 business days*	652.00€
DIM-DMC101037.500	500 µg	-	-	7 - 16 business days*	1,960.00€

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Protein function: Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower... more

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Product information "Anti-TNFRSF1B antibody(8C4), IgG1 Chimeric mAb"

Protein function: Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity. [The UniProt Consortium]

Keywords:	Anti-CD120b, Anti-p75, Anti-p75TNFR, Anti-TBPII, Anti-TNF-R-II, Anti-TNF-R75, Anti-TNFBR, Anti-TNFR1B, Anti-TNFR2, Anti-TNFR80, Anti-TNFRSF1B antibody(8C4), IgG1 Chimeric mAb
Supplier:	DIMA
Supplier-Nr:	DMC101037

Properties

Antibody Type:	Monoclonal
Clone:	8C4
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Format:	Lyophilized

Database Information

KEGG ID :	K05141 \| Matching products
UniProt ID :	P20333 \| Matching products
Gene ID :	GeneID 7133 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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