Anti-TNFRSF10B (tilogotamab biosimilar) mAb, biotinylated

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
DIM-BME100698B.50	50 µg		-	-	7 - 16 business days*		145.00€
DIM-BME100698B.100	100 µg		-	-	7 - 16 business days*		291.00€

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Research use only. Protein function: Receptor for the cytotoxic ligand TNFSF10/TRAIL... more

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Product information "Anti-TNFRSF10B (tilogotamab biosimilar) mAb, biotinylated"

Research use only. Protein function: Receptor for the cytotoxic ligand TNFSF10/TRAIL (PubMed:10549288). The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis. [The UniProt Consortium]

Keywords:	GEN-1029,GEN1029,GEN 1029, Anti-DR5, Anti-CD262, Anti-TRAIL-R2, Anti-TNFRSF10B, Anti-TRAIL receptor 2, Anti-Death receptor 5, Anti-TNF-related apoptosis-inducing ligand receptor 2, Anti-Tumor necrosis factor receptor superfamily member 10B
Supplier:	DIMA
Supplier-Nr:	BME100698B

Properties

Antibody Type:	Monoclonal
Conjugate:	Biotin
Species reactivity:	human
Format:	Lyophilized

Database Information

KEGG ID :	K04722 \| Matching products
UniProt ID :	O14763 \| Matching products
Gene ID :	GeneID 8795 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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