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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ARG23004.100 | 100 µg | - | - |
10 - 15 business days* |
535.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted... more
Product information "Anti-TNF alpha, clone CC327"
Protein function: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces GKAP42 protein degradation in adipocytes which is partially responsible for TNF-induced insulin resistance. Plays a role in angiogenesis by inducing VEGF production synergistically with IL1B and IL6. {ECO:0000250, UniProtKB:P01375, ECO:0000250, UniProtKB:P06804}. [The UniProt Consortium]
| Keywords: | Anti-TNF, Anti-NTF, Anti-TNFA, Anti-ICD1, Anti-ICD2, Anti-TNF-a, Anti-Cachectin, Anti-TNF-alpha, Anti-C-domain 1, Anti-C-domain 2, Anti-N-terminal fragment, Anti-Tumor necrosis factor, Anti-Intracellular domain 1, Anti-Intracellular domain 2, Anti-Tumor n |
| Supplier: | Arigo Biolaboratories |
| Supplier-Nr: | ARG23004 |
Properties
| Application: | ELISA, FC |
| Antibody Type: | Monoclonal |
| Clone: | CC327 |
| Conjugate: | No |
| Host: | Mouse |
| Species reactivity: | bovine, deer |
| Immunogen: | Recombinant Bovine TNF alpha |
| MW: | 26 kD |
| Format: | Purified |
Database Information
| KEGG ID : | K03156 | Matching products |
| UniProt ID : | Q06599 | Matching products |
| Gene ID : | GeneID 280943 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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