Anti-TMPRSS2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA035787.25	25 µl		-		7 - 10 business days*		330.00€
ATA-HPA035787.100	100 µl		-		7 - 10 business days*		463.00€

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Protein function: Plasma membrane-anchored serine protease that participates in proteolytic... more

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Product information "Anti-TMPRSS2"

Protein function: Plasma membrane-anchored serine protease that participates in proteolytic cascades of relevance for the normal physiologic function of the prostate (PubMed:25122198). Androgen-induced TMPRSS2 activates several substrates that include pro-hepatocyte growth factor/HGF, the protease activated receptor-2/F2RL1 or matriptase/ST14 leading to extracellular matrix disruption and metastasis of prostate cancer cells (PubMed:15537383, PubMed:26018085, PubMed:25122198). In addition, activates trigeminal neurons and contribute to both spontaneous pain and mechanical allodynia. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 66% and to rat: 66%

Keywords:	Anti-PRSS10, EC=3.4.21.-
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA035787

Properties

Application:	IHC, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: GSPPAIGPYY ENHGYQPENP YPAQPTVVPT VYEVHPAQYY PSPVPQYAPR VLTQASNPVV CTQPKSPSGT VCTSKT (ATA-APrEST87138)