Anti-TLK1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A301-253A-T	10 µl (2 µg)		-		2 - 8 business days*		178.00€
A301-253A	100 µl		-		2 - 8 business days*		630.00€

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Protein function: Rapidly and transiently inhibited by phosphorylation following the generation... more

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Product information "Anti-TLK1"

Protein function: Rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S- phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly. Isoform 3 phosphorylates and enhances the stability of the t-SNARE SNAP23, augmenting its assembly with syntaxin. Isoform 3 protects the cells from the ionizing radiation by facilitating the repair of DSBs. In vitro, phosphorylates histone H3 at 'Ser-10'. [The UniProt Consortium]

Keywords:	Anti-TLK1, Anti-PKU-beta, Anti-KIAA0137, EC=2.7.11.1, Anti-Tousled-like kinase 1, Anti-Serine/threonine-protein kinase tousled-like 1
Supplier:	Bethyl Laboratories
Supplier-Nr:	A301-253A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse (Expected: rat, dog, horse, rabbit, pig, panda, orangutan, rhesus monkey, gorilla, chimpanzee, white-tufted-ear marmoset, crab-eating macaque, naked mole rat, small-eared galago, northern white-cheeked gibbon)
Immunogen:	synthetic peptide. The epitope recognized by A301-253A-T maps to a region between residue 716 and 766 of human tousled-like kinase 1 using the numbering given in entry NP_036422.3 (GeneID 9874).
Format:	Antigen Affinity Purified