Anti-TIPRL

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-HPA027995.25 25 µl -

7 - 10 business days*

246.00€
ATA-HPA027995.100 100 µl -

7 - 10 business days*

491.00€
 
Protein function: May be a allosteric regulator of serine/threonine-protein phosphatase 2A... more
Product information "Anti-TIPRL"
Protein function: May be a allosteric regulator of serine/threonine-protein phosphatase 2A (PP2A). Isoform 1 inhibits catalytic activity of the PP2A(D) core complex in vitro. The PP2A(C):TIPRL complex does not show phosphatase activity. Acts as negative regulator of serine/threonine- protein phosphatase 4 probably by inhibiting the formation of the active PPP4C:PPP4R2 complex, the function is proposed to implicate it in DNA damage response by promoting H2AX phosphorylated on Ser-140 (gamma-H2AX). May play a role in the regulation of ATM/ATR signaling pathway controlling DNA replication and repair. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 97% and to rat: 97%
Keywords: Anti-TIP, Anti-TIPRL, Anti-TIP41-like protein, Anti-Type 2A-interacting protein, Anti-Putative MAPK-activating protein PM10
Supplier: Atlas Antibodies
Supplier-Nr: HPA027995

Properties

Application: ICC, IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: SHRDFCFGPW KLTASKTHIM KSADVEKLAD ELHMPSLPEM MFGDNVLRIQ HGSGFGIEFN ATDALRCVNN YQGMLK (ATA-APrEST76834)

Database Information

KEGG ID : K17607 | Matching products
UniProt ID : O75663 | Matching products
Gene ID : GeneID 261726 | Matching products
Protein Atlas Nr. : ENSG00000143155

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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