Anti-TIPIN

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A301-474A-T	10 µl (2 µg)		-		2 - 8 business days*		164.00€
A301-474A	100 µl		-		2 - 8 business days*		588.00€

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Protein function: Plays an important role in the control of DNA replication and the maintenance... more

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Product information "Anti-TIPIN"

Protein function: Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Important for cell survival after DNA damage or replication stress. May be specifically required for the ATR-CHEK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light. Forms a complex with TIMELESS and this complex regulates DNA replication processes under both normal and stress conditions, stabilizes replication forks and influences both CHEK1 phosphorylation and the intra-S phase checkpoint in response to genotoxic stress. [The UniProt Consortium]

Keywords:	Anti-TIPIN, Anti-TIMELESS-interacting protein
Supplier:	Bethyl Laboratories
Supplier-Nr:	A301-474A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: rhesus monkey, gorilla, chimpanzee, crab-eating macaque, northern white-cheeked gibbon)
Immunogen:	synthetic peptide. The epitope recognized by A301-474A-T maps to a region between residue 251 and 301 of human TIMELESS interacting protein using the numbering given in entry NP_060328.1 (GeneID 54962).
Format:	Antigen Affinity Purified