Anti-TIMP2, clone SPM356

Anti-TIMP2, clone SPM356
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V3376-20UG 20 µg - -

3 - 10 business days

251.00€
NSJ-V3376-100UG 100 µg - -

3 - 10 business days

541.00€
 
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide. It recognizes a... more
Product information "Anti-TIMP2, clone SPM356"
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide. It recognizes a protein of 21kDa, identified as tissue inhibitor of metalloproteinases 2 (TIMP2). It is closely related to TIMP1 and shows the highest binding affinity to both the latent (pro) and active forms of 72kDa Type IV collagenase (also known as MMP2 or gelatinase A). It also has affinity for the active form of 92kDa Type IV collagenase (also known as MMP9 or gelatinase B). TIMP2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells. Protein function: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19. [The UniProt Consortium]
Keywords: Anti-TIMP2, Anti-TIMP-2, Anti-CSC-21K, Anti-Metalloproteinase inhibitor 2, Anti-Tissue inhibitor of metalloproteinases 2, TIMP2 Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: V3376-20UG

Properties

Application: IHC (paraffin), IF, WB
Antibody Type: Monoclonal
Clone: SPM356
Conjugate: No
Host: Mouse
Reactivity: Human, Mouse, Rat
Immunogen: An amino acid sequence from the N-terminal region of the human protein was used as the immunogen for this TIMP2 antibody.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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