Anti-TIMP-1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG55639.100	100 µl		-	-	6 - 14 business days*		616.00€

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Protein function: Metalloproteinase inhibitor that functions by forming one to one complexes with... more

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Product information "Anti-TIMP-1"

Protein function: Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Mediates erythropoiesis in vitro, but, unlike IL3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. [The UniProt Consortium]

Keywords:	Anti-EPA, Anti-CLGI, Anti-TIMP1, Anti-TIMP-1, Anti-Collagenase inhibitor, Anti-Metalloproteinase inhibitor 1, Anti-Erythroid-potentiating activity, Anti-Fibroblast collagenase inhibitor, Anti-Tissue inhibitor of metalloproteinases 1
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG55639

Properties

Application:	WB, IHC (paraffin), FC, ICC, IF
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	KLH-conjugated synthetic peptide around aa. 41-70 of Human TIMP-1
MW:	23 kD
Format:	Ammonium Sulfate Precipitated