Anti-Thyroglobulin

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-KC-1379.50	50 µl		-	-	10 - 15 business days*		206.00€
ABS-KC-1379.100	100 µl		-	-	10 - 15 business days*		295.00€

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Protein function: Acts as a substrate for the production of iodinated thyroid hormones thyroxine... more

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Product information "Anti-Thyroglobulin"

Protein function: Acts as a substrate for the production of iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3) (PubMed:32025030, PubMed:17532758). The synthesis of T3 and T4 involves iodination of selected tyrosine residues of TG/thyroglobulin followed by their oxidative coupling in the thyroid follicle lumen (PubMed:32025030). Following TG re-internalization and lysosomal-mediated proteolysis, T3 and T4 are released from the polypeptide backbone leading to their secretion into the bloodstream (PubMed:32025030). One dimer produces 7 thyroid hormone molecules (PubMed:32025030). [The UniProt Consortium]

Keywords:	Anti-Thyroglobulin, Anti-Tg, TG Antibody
Supplier:	Absea
Supplier-Nr:	KC-1379

Properties

Application:	IHC
Antibody Type:	Monoclonal
Clone:	19B11
Conjugate:	No
Host:	Mouse
Species reactivity:	human
Immunogen:	Recombinant human TG
Format:	Solution

Database Information

KEGG ID :	K10809 \| Matching products
UniProt ID :	P01266 \| Matching products
Gene ID :	GeneID 7038 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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