Anti-Thrombomodulin / CD141, clone THBD/1782

Anti-Thrombomodulin / CD141, clone THBD/1782
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V3324-20UG 20 µg - -

3 - 10 business days

251.00€
NSJ-V3324-100UG 100 µg - -

3 - 10 business days

541.00€
 
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide. It recognizes a... more
Product information "Anti-Thrombomodulin / CD141, clone THBD/1782"
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide. It recognizes a protein of 75kDa, identified as Thrombomodulin. Thrombomodulin is a transmembrane glycoprotein with natural anticoagulant properties. It is normally expressed by a restricted number of cells, such as endothelial and mesothelial cells. In addition, synovial lining and syncytio-trophoblasts of placenta also express thrombomodulin. This protein is present in almost all of benign vascular tumors and majority of malignant vascular tumors (Kaposi s sarcoma, angiosarcoma, and epithelioid hemangioendothelioma). Hence, anti-thrombomodulin serves as a sensitive marker for lymphatic endothelial cells and their tumors. Recently, thrombomodulin antibody has been used for mesothelial cells and malignant mesotheliomas. Protein function: Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated. [The UniProt Consortium]
Keywords: Anti-TM, Anti-THRM, Anti-THBD, Anti-CD141, Anti-Fetomodulin, Anti-Thrombomodulin, Thrombomodulin Antibody / CD141
Supplier: NSJ Bioreagents
Supplier-Nr: V3324-20UG

Properties

Application: IHC (paraffin), FC, IF, ELISA
Antibody Type: Monoclonal
Clone: THBD/1782
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: Human recombinant partial protein corresponding to amino acids 69-194 was used as the immunogen for this Thrombomodulin antibody.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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