Anti-THOC3

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA042764.100	100 µl		-		7 - 10 business days*		491.00€

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Protein function: Required for efficient export of polyadenylated RNA and spliced mRNA. Acts as... more

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Product information "Anti-THOC3"

Protein function: Required for efficient export of polyadenylated RNA and spliced mRNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap- dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 100% and to rat: 100%

Keywords:	Anti-Tho3, Anti-THOC3, Anti-hTREX45, Anti-TEX1 homolog, Anti-THO complex subunit 3
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA042764

Properties

Application:	ICC, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: KTHRSKAEEQ FKFEVNEISW NNDNNMFFLT NGNGCINILS YPELKPVQSI NAHPSNCICI KFDPMGKYFA TGSADALV (ATA-APrEST82636)