Anti-TGF-beta, clone 1D11.16.8

Anti-TGF-beta, clone 1D11.16.8
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V2889SAF-100UG 100 µg - -

3 - 10 business days

541.00€
 
1 mg/ml in sterile PBS, BSA free, sodium azide free. This mAb recognizes TGF beta 1, 2 and 3.... more
Product information "Anti-TGF-beta, clone 1D11.16.8"
1 mg/ml in sterile PBS, BSA free, sodium azide free. This mAb recognizes TGF beta 1, 2 and 3. Three TGFbs have been identified in mammals. TGFb1, TGFb2 and TGFb3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecules. Biologically active TGFb requires dimerization of the monomers (usually homodimers) and release of the latent peptide portion. Overall, the mature region of the TGFb3 protein has approximately 80% identity to the mature region of both TGFb1 and TGFb2. However, the NH2 terminals or precursor regions of their molecules share only 27% sequence identity. TGFb's inhibit the growth of epithelial cells and stimulate the growth of mesenchymal cells. Protein function: TGF-beta 2 has suppressive effects on interleukin-2 dependent T-cell growth. [The UniProt Consortium]
Keywords: Anti-MGF, Anti-TGFB2, Anti-TGF-beta-2, Anti-Milk growth factor, Anti-Transforming growth factor beta-2, TGF-beta Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: V2889SAF-100UG

Properties

Application: IHC (paraffin), FA-Cytokine Neutralization
Antibody Type: Monoclonal
Clone: 1D11.16.8
Conjugate: No
Host: Mouse
Reactivity: Human, Monkey, Bovine, Dog, Mouse, Rat, Hamster
Immunogen: Bovine TGF-beta2 protein
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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