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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ELK-ES12753.50 | 50 µl | - | - |
10 - 15 business days* |
173.00€
|
||
| ELK-ES12753.100 | 100 µl | - | - |
10 - 15 business days* |
290.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: S-adenosyl-L-methionine-dependent rRNA methyltransferase which may methylate... more
Product information "Anti-TFB2M"
Protein function: S-adenosyl-L-methionine-dependent rRNA methyltransferase which may methylate two specific adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 12S mitochondrial rRNA (Probable). Component of the mitochondrial transcription initiation complex, composed at least of TFB2M, TFAM and POLRMT that is required for basal transcription of mitochondrial DNA (PubMed:29149603, PubMed:12068295, PubMed:20410300, PubMed:15526033). In this complex, TFAM recruits POLRMT to a specific promoter whereas TFB2M induces structural changes in POLRMT to enable promoter opening and trapping of the DNA non- template strand (PubMed:29149603, PubMed:15526033). Stimulates transcription independently of the methyltransferase activity (PubMed:12897151). [The UniProt Consortium] Recommended dilutions: WB 1:500-2000. Cellular localization: Mitochondrion.
| Keywords: | Anti-hTFB2M, Anti-mtTFB2, Anti-h-mtTFB, Anti-NS5ATP5, Anti-h-mtTFB2, Anti-HCV NS5A-transactivated protein 5, Anti-Mitochondrial 12S rRNA dimethylase 2, Anti-Mitochondrial transcription factor B2, Anti-Dimethyladenosine transferase 2, mitochondrial, TFB2M |
| Supplier: | ELK Biotechnology |
| Supplier-Nr: | ES12753 |
Properties
| Application: | WB |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
| Immunogen: | Synthesized peptide derived from human TFB2M AA range: 192-242 |
| Format: | Purified |
Database Information
| KEGG ID : | K17653 | Matching products |
| UniProt ID : | Q9H5Q4 | Matching products |
| Gene ID : | GeneID 64216 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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