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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-F40574-0.08ML | 80 µl | - | - |
3 - 10 business days* |
326.00€
|
||
NSJ-F40574-0.4ML | 400 µl | - | - |
3 - 10 business days* |
702.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
In 1X PBS, pH 7.4, with 0.09% sodium azide. This gene encodes a mitochondrial transcription... more
Product information "Anti-TFAM"
In 1X PBS, pH 7.4, with 0.09% sodium azide. This gene encodes a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this gene product is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns-Sayre syndrome was produced when expression of this gene was eliminated by targeted disruption in heart and muscle cells. Protein function: Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind DNA. Bends the mitochondrial light strand promoter DNA into a U-turn shape via its HMG boxes. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA. [The UniProt Consortium]
Keywords: | Anti-TCF6, Anti-TFAM, Anti-TCF-6, Anti-MtTF1, Anti-mtTFA, Anti-Transcription factor 6, Anti-Transcription factor 6-like 2, Anti-Mitochondrial transcription factor 1, Anti-Transcription factor A, mitochondrial, TFAM Antibody |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | F40574 |
Properties
Application: | IHC, FC, IF, WB, ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | A portion of amino acids 216-246 from the human protein was used as the immunogen for this TFAM antibody. |
Format: | Purified |
Database Information
KEGG ID : | K11830 | Matching products |
UniProt ID : | Q00059 | Matching products |
Gene ID | GeneID 7019 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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