Anti-TEM7

PTM:N-glycosylated.,similarity:Belongs to the plexin family.,subunit:May interact with cortactin.,tissue specificity:Detected in endothelial cells from colorectal cancer, and in endothelial cells from primary cancers of the lung, liver, pancreas, breast and brain. Not detectable in endothelial cells from normal tissue., Protein function: Plays a critical role in endothelial cell capillary morphogenesis. [The UniProt Consortium] Recommended dilutions: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.. Cellular localization: [Isoform 1]: Cell membrane, Single-pass type I membrane protein. Cell junction, tight junction. Localized predominantly at the tight junctions of vascular endothelial cells and to a lesser extent at the luminal surface of vascular endothelial cells., [Isoform 2]: Secreted ., [Isoform 3]: Secreted ., [Isoform 4]: Cytoplasm .