Anti-TDP43

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A303-223A-T	10 µl (2 µg)		-		2 - 8 business days*		164.00€
A303-223A	100 µl		-		2 - 8 business days*		588.00€

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Protein function: DNA and RNA-binding protein which regulates transcription and splicing.... more

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Product information "Anti-TDP43"

Protein function: DNA and RNA-binding protein which regulates transcription and splicing. Involved in the regulation of CFTR splicing. It promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis. May also be involved in microRNA biogenesis, apoptosis and cell division. Can repress HIV-1 transcription by binding to the HIV-1 long terminal repeat. Stabilizes the low molecular weight neurofilament (NFL) mRNA through a direct interaction with the 3' UTR. [The UniProt Consortium]

Keywords:	Anti-TDP43, Anti-TARDBP, Anti-TDP-43, Anti-TAR DNA-binding protein 43
Supplier:	Bethyl Laboratories
Supplier-Nr:	A303-223A

Properties

Application:	WB, IP, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse (Expected: orangutan)
Immunogen:	synthetic peptide. The epitope recognized by A303-223A-T maps to a region between residue 150 and 200 of human TAR DNA-Binding Protein 43 using the numbering given in entry NP_031401.1 (GeneID 23435).
Format:	Antigen Affinity Purified