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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ELK-ES10639.50 | 50 µl | - | - |
10 - 14 business days* |
173.00€
|
||
| ELK-ES10639.100 | 100 µl | - | - |
10 - 14 business days* |
290.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
function:May act as a 'capping' or 'branching' protein for keratin filaments in the cell... more
Product information "Anti-TCHP"
function:May act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. May regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells.,similarity:Belongs to the TCHP family.,subunit:Interacts specifically with keratin proteins including, KRT5, KRT6A, KRT8, KRT14, KRT16 and KRT18., Protein function: Tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress. Inhibits cell growth in bladder and prostate cancer cells by a down-regulation of HSPB1 by inhibiting its phosphorylation. May act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. May regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells (PubMed:15731013, PubMed:18931701). Is a negative regulator of ciliogenesis (PubMed:25270598). [The UniProt Consortium] Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000. Cellular localization: Cytoplasm, cytoskeleton . Cytoplasm . Cell membrane . Mitochondrion . Cell junction, desmosome .
| Keywords: | Anti-Mitostatin, Anti-Protein TCHP, Anti-Tumor suppressor protein, Anti-Trichoplein keratin filament-binding protein, Anti-Mitochondrial protein with oncostatic activity, TCHP rabbit pAb |
| Supplier: | ELK Biotechnology |
| Supplier-Nr: | ES10639 |
Properties
| Application: | WB, ELISA |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human, rat, mouse, |
| Immunogen: | Synthesized peptide derived from part region of human protein |
| MW: | 54 kD |
| Format: | Purified |
Database Information
| KEGG ID : | K16811 | Matching products |
| UniProt ID : | Q9BT92 | Matching products |
| Gene ID : | GeneID 84260 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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