Anti-TCF25

Anti-TCF25
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ELK-ES10373.50 50 µl - -

10 - 14 business days*

173.00€
ELK-ES10373.100 100 µl - -

10 - 14 business days*

290.00€
 
TCF25 is a member of the basic helix-loop-helix (bHLH) family of transcription factors that are... more
Product information "Anti-TCF25"
TCF25 is a member of the basic helix-loop-helix (bHLH) family of transcription factors that are important in embryonic development (Steen and Lindholm, 2008 [PubMed 18068114]).[supplied by OMIM, Sep 2008], Protein function: Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation (PubMed:30244831). In the RQC complex, required to promote formation of 'Lys-48'-linked polyubiquitin chains during ubiquitination of incompletely synthesized proteins by LTN1 (PubMed:30244831). Also acts as a transcriptional repressor: represses transcription of SRF in vitro and so may play a role in heart development (PubMed:16574069). May play a role in cell death control. [The UniProt Consortium] Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000. Cellular localization: Nucleus . Some staining in the cytosol.
Keywords: Anti-TCF-25, Anti-Transcription factor 25, Anti-Nuclear localized protein 1, Anti-Ribosome quality control complex subunit TCF25, TCF25 rabbit pAb
Supplier: ELK Biotechnology
Supplier-Nr: ES10373

Properties

Application: WB, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse
Immunogen: Synthesized peptide derived from part region of human protein
MW: 74 kD
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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