Anti-TACI / Transmembrane activator and CAML interactor

Anti-TACI / Transmembrane activator and CAML interactor
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-RQ4341 100 µg - -

3 - 10 business days*

755.00€
 
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Transmembrane activator and CAML... more
Product information "Anti-TACI / Transmembrane activator and CAML interactor"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Transmembrane activator and CAML interactor (TACI), also known as tumor necrosis factor receptor superfamily member 13B (TNFRSF13B) is a protein that in humans is encoded by the TNFRSF13B gene. The protein encoded by this gene is a lymphocyte-specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML). The protein induces activation of the transcription factors NFAT, AP1, and NF-kappa-B and plays a crucial role in humoral immunity by interacting with a TNF ligand. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Protein function: Receptor for TNFSF13/APRIL and TNFSF13B/TALL1/BAFF/BLYS that binds both ligands with similar high affinity. Mediates calcineurin- dependent activation of NF-AT, as well as activation of NF-kappa-B and AP-1. Involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. [The UniProt Consortium]
Keywords: Anti-TACI, Anti-CD267, Anti-TNFRSF13B, Anti-Transmembrane activator and CAML interactor, Anti-Tumor necrosis factor receptor superfamily member 13B, TACI Antibody / Transmembrane activator and CAML interactor
Supplier: NSJ Bioreagents
Supplier-Nr: RQ4341

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: recombinant human protein corresponding to amino acids M1-S165
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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