Item number Size Datasheet Manual SDS Delivery time Quantity Price
A301-438A-T 20 µl (2 blots) -

3 - 9 business days*

A301-438A-M 100 µl (10 blots) -

3 - 9 business days*

A301-438A 100 µl (20 µg) -

3 - 9 business days*

TAB182 (tankyrase 1-binding protein of 182 kDa) was identified in a two-hybrid screen in search... more
Product information "Anti-TAB182"
TAB182 (tankyrase 1-binding protein of 182 kDa) was identified in a two-hybrid screen in search of tankyrase 1-interacting proteins. Tankyrase 1 is a poly (ADP-ribose) polymerase (PARP) that ribosylates the negative regulator of telomere length, TRF1 (telomere-repeat binding factor). Ribosylation of TRF1 has been shown to result in the inhibition of TRF1 binding and an induction of telomere elongation. TAB182 and TRF1 bind multiple discrete and overlapping sites of the tankyrase 1 ankyrin domain. This finding suggests that TAB182 may act as a scaffold to mediate higher order protein complex formation at telomeres. TAB182 has also been suggested to serve a role in the cytoplasm as it has been found to localize to the cytoplasmic cortical actin network. Alternate names for TAB182 include TNKS1BP1, KIAA1741, and FLJ45975.
Keywords: Anti-KIAA1741, Anti-TNKS1BP1, Anti-182 kDa tankyrase-1-binding protein
Supplier: Bethyl Laboratories
Supplier-Nr: A301-438A


Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human (Expected: Orangutan, Rhesus Monkey, Gorilla, Chimpanzee, White-tufted-ear Marmoset, Crab-eating Macaque, Northern White-cheeked Gibbon)
Immunogen: synthetic peptide. The epitope recognized by A301-438A-T maps to a region between residue 350 and 400 of human tankyrase 1-binding protein of 182 kDa using the numbering given in entry NP_203754.2 (GeneID 85456).
Format: Antigen Affinity Purified

Database Information

UniProt ID : Q9C0C2 | Find alternatives
Gene ID GeneID 85456 | Find alternatives

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Our products are for laboratory research use only: Not for administration to humans!
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