Anti-SUZ12

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-HPA057436.25 25 µl -

7 - 10 business days*

330.00€
ATA-HPA057436.100 100 µl -

7 - 10 business days*

463.00€
 
Protein function: Polycomb group (PcG) protein. Component of the PRC2 complex, which methylates... more
Product information "Anti-SUZ12"
Protein function: Polycomb group (PcG) protein. Component of the PRC2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene (PubMed:15225548, PubMed:15231737, PubMed:15385962, PubMed:16618801, PubMed:17344414, PubMed:18285464, PubMed:28229514, PubMed:29499137, PubMed:31959557). The PRC2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems (PubMed:12435631, PubMed:12351676, PubMed:15385962, PubMed:15099518, PubMed:15225548, PubMed:15684044, PubMed:16431907, PubMed:18086877, PubMed:18285464). Genes repressed by the PRC2 complex include HOXC8, HOXA9, MYT1 and CDKN2A (PubMed:15231737, PubMed:16618801, PubMed:17200670, PubMed:31959557). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 96% and to rat: 90%
Keywords: Anti-SUZ12, Anti-CHET9, Anti-ChET 9 protein, Anti-Polycomb protein SUZ12, Anti-Joined to JAZF1 protein, Anti-Suppressor of zeste 12 protein homolog, Anti-Chromatin precipitated E2F target 9 protein
Supplier: Atlas Antibodies
Supplier-Nr: HPA057436

Properties

Application: IHC, WB, ICC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: NKPGSVKPTQ TIAVKESLTT DLQTRKEKDT PNENRQKLRI FYQFLYNNNT RQQTEARDDL HCPWCTLNCR KLYSLLKHLK LCHSRFIFNY VYHPKGARID VSINECYDGS YAGNPQDIHR QPGFAFSRNG PVKRTPIT (ATA-APrEST86710)

Database Information

KEGG ID : K11463 | Matching products
UniProt ID : Q15022 | Matching products
Gene ID : GeneID 23512 | Matching products
Protein Atlas Nr. : ENSG00000178691

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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