Anti-SUPV3L1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA038405.25	25 µl		-		7 - 10 business days*		369.00€
ATA-HPA038405.100	100 µl		-		7 - 10 business days*		491.00€

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Protein function: Major helicase player in mitochondrial RNA metabolism. Component of the... more

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Product information "Anti-SUPV3L1"

Protein function: Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. Involved in the degradation of non-coding mitochondrial transcripts (MT-ncRNA) and tRNA-like molecules (PubMed:29967381). ATPase and ATP-dependent multisubstrate helicase, able to unwind double-stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria, regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates. Also implicated in recombination and chromatin maintenance pathways. May protect cells from apoptosis. Associates with mitochondrial DNA. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 100% and to rat: 100%

Keywords:	Anti-SUV3, Anti-SUPV3L1, Anti-SUV3-like protein 1, Anti-Suppressor of var1 3-like protein 1, Anti-ATP-dependent RNA helicase SUPV3L1, mitochondrial
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA038405

Properties

Application:	IHC, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: IQHIPLSLRV RYVFCTAPIN KKQPFVCSSL LQFARQYSRN EPLTFAWLRR YIKWPLLPPK NIKDLMDLEA VH (ATA-APrEST80319)