Anti-STON2

This gene encodes a protein which is a membrane protein involved in regulating endocytotic complexes. The protein product is described as one of the clathrin-associated sorting proteins, adaptor molecules which ensure specific proteins are internalized. The encoded protein has also been shown to participate in synaptic vesicle recycling through interaction with synaptotagmin 1 required for neurotransmission. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012], Protein function: Adapter protein involved in endocytic machinery. Involved in the synaptic vesicle recycling. May facilitate clathrin-coated vesicle uncoating. [The UniProt Consortium] Recommended dilutions: WB 1:500-2000, IF/ICC 1:50-200,ELISA 1:2000-20000,IHC-p 1:50-200. Cellular localization: Cytoplasm . Membrane . Cell junction, synapse, synaptosome . Some fraction is membrane-associated.