Anti-STK36

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA027453.25	25 µl		-		7 - 10 business days*		335.00€
ATA-HPA027453.100	100 µl		-		7 - 10 business days*		446.00€

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Protein function: Serine/threonine protein kinase which plays an important role in the sonic... more

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Product information "Anti-STK36"

Protein function: Serine/threonine protein kinase which plays an important role in the sonic hedgehog (Shh) pathway by regulating the activity of GLI transcription factors (PubMed:10806483). Controls the activity of the transcriptional regulators GLI1, GLI2 and GLI3 by opposing the effect of SUFU and promoting their nuclear localization (PubMed:10806483). GLI2 requires an additional function of STK36 to become transcriptionally active, but the enzyme does not need to possess an active kinase catalytic site for this to occur (PubMed:10806483). Required for postnatal development, possibly by regulating the homeostasis of cerebral spinal fluid or ciliary function. Essential for construction of the central pair apparatus of motile cilia. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 82% and to rat: 84%

Keywords:	EC=2.7.11.1, Anti-Fused homolog, Anti-Serine/threonine-protein kinase 36
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA027453

Properties

Application:	ICC, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: EMWTVLWHRF SMVLRLPEEA SAQEGELSLS SPPSPEPDWT LISPQGMAAL LSLAMATFTQ EPQLCLSCLS QHGSILMSIL KH (ATA-APrEST77833)