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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-RQ4523 | 100 µg | - | - |
3 - 10 business days* |
755.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Cystatin B (CSTB), also called STFB, is a... more
Product information "Anti-Stefin B, clone 2B6"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Cystatin B (CSTB), also called STFB, is a small protein that is a member of the superfamily of cysteine protease inhibitors. It has been isolated from human spleen and liver and its amino acid sequence has been fully determined. The cystatin B gene is located on 21q22.3. It is widely distributed and is localized mostly intracellularly, but has been found extracellularly. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. Its role is thought to be as a protector against the proteinases leaking from lysosomes. A cystatin B multiprotein complex might have a specific cerebellar function, and that the loss of this function might contribute to the etiopathogenesis of EPM1. Upon differentiation to myotubes, CSTB becomes excluded from the nucleus and lysosomes, suggesting that the subcellular distribution of CSTB is dependent on the differentiation status of the cell. Protein function: This is an intracellular thiol proteinase inhibitor. Tightly binding reversible inhibitor of cathepsins L, H and B. [The UniProt Consortium]
Keywords: | Anti-CSTB, Anti-CST6, Anti-CPI-B, Anti-Stefin-B, Anti-Cystatin-B, Anti-Liver thiol proteinase inhibitor, Stefin B Antibody |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | RQ4523 |
Properties
Application: | WB, IHC (paraffin), FC |
Antibody Type: | Monoclonal |
Clone: | 2B6 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Human Stefin B recombinant protein (amino acids M1-F98) |
Format: | Purified |
Database Information
KEGG ID : | K13907 | Matching products |
UniProt ID : | P04080 | Matching products |
Gene ID | GeneID 1476 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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