Anti-STAT3

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
600-401-GH6S	25 µl		-	-	6 - 10 business days*		180.00€

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Anti-STAT3 was affinity purified from monospecific antiserum by immunoaffinity chromatography.... more

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Product information "Anti-STAT3"

Anti-STAT3 was affinity purified from monospecific antiserum by immunoaffinity chromatography. This antibody reacts with all STAT3 modifications. Cross-reactivity is seen against STAT1 and STAT4. BLAST analysis was used to suggest cross-reactivity with Human, mouse, and rat. Cross-reactivity with STAT3 from other sources has not been determined. Protein function: Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)- responsive elements identified in the promoters of various acute- phase protein genes. Activated by IL31 through IL31RA. Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G. [The UniProt Consortium]

Keywords:	Anti-APRF, Anti-STAT3, Anti-Acute-phase response factor, Anti-Signal transducer and activator of transcription 3
Supplier:	Rockland Immunochemicals
Supplier-Nr:	600-401-GH6S

Properties

Application:	ELISA, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Synthetic monomethylated or asymmetric dimethylated peptides surrounding Arginine 31 of human STAT.
Format:	Purified