Anti-SRGP1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ELK-ES12955.50	50 µl		-	-	10 - 14 business days*		173.00€
ELK-ES12955.100	100 µl		-	-	10 - 14 business days*		290.00€

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The protein encoded by this gene is a GTPase activator, working with the GTPase CDC42 to... more

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Product information "Anti-SRGP1"

The protein encoded by this gene is a GTPase activator, working with the GTPase CDC42 to negatively regulate neuronal migration. The encoded protein interacts with the transmembrane receptor ROBO1 to inactivate CDC42. [provided by RefSeq, Sep 2016], Protein function: GTPase-activating protein for RhoA and Cdc42 small GTPases. Together with CDC42 seems to be involved in the pathway mediating the repulsive signaling of Robo and Slit proteins in neuronal migration. SLIT2, probably through interaction with ROBO1, increases the interaction of SRGAP1 with ROBO1 and inactivates CDC42. [The UniProt Consortium] Recommended dilutions: WB 1:500-2000. Cellular localization: cytoplasm,cytosol,

Keywords:	Anti-srGAP1, Anti-SRGAP1, Anti-ARHGAP13, Anti-Rho GTPase-activating protein 13, Anti-SLIT-ROBO Rho GTPase-activating protein 1, SRGP1 rabbit pAb
Supplier:	ELK Biotechnology
Supplier-Nr:	ES12955

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse
Immunogen:	Synthesized peptide derived from human SRGP1 AA range: 159-209
Format:	Purified