Anti-SRGN

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA000759.25	25 µl		-		7 - 10 business days*		330.00€
ATA-HPA000759.100	100 µl		-		7 - 10 business days*		463.00€

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Protein function: Plays a role in formation of mast cell secretory granules and mediates storage... more

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Product information "Anti-SRGN"

Protein function: Plays a role in formation of mast cell secretory granules and mediates storage of various compounds in secretory vesicles. Required for storage of some proteases in both connective tissue and mucosal mast cells and for storage of granzyme B in T-lymphocytes. Plays a role in localizing neutrophil elastase in azurophil granules of neutrophils. Mediates processing of MMP2. Plays a role in cytotoxic cell granule- mediated apoptosis by forming a complex with granzyme B which is delivered to cells by perforin to induce apoptosis. Regulates the secretion of TNF-alpha and may also regulate protease secretion. Inhibits bone mineralization. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 53% and to rat: 55%

Keywords:	Anti-PRG, Anti-P.PG, Anti-SRGN, Anti-Serglycin, Anti-Platelet proteoglycan core protein, Anti-Hematopoietic proteoglycan core protein, Anti-Secretory granule proteoglycan core protein
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA000759

Properties

Application:	IHC, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: MQKLLKCSRL VLALALILVL ESSVQGYPTR RARYQWVRCN PDSNSANCLE EKGPMFELLP GESNKIPRLR TDLFPKTRIQ DLNRIFPLSE DYSGSGFGSG SGSGSGSGSG FLTEMEQDYQ LVDE (ATA-APrEST76124)